Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The oral form of the drug, called sucroferric oxyhydroxide and used . 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ * Sex and gender exist on spectrums. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Some may be a better fit for you than others. As with all medications, the cost of Injectafer can vary. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. In one study, people were given either Injectafer or an iron replacement drug called Venofer. Its possible that after getting two doses of Injectafer, your anemia may go away completely. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. (A medication class describes a group of drugs that work in the same way.). Diarrhea. This may be helped by giving the medication more slowly or at a lower dose. You may also need to monitor your blood pressure at home. Its caused by your body not having enough iron, which is needed to make hemoglobin. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. People with IDA have low blood levels of hemoglobin. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. IQVIA [NSP Audit from MAT November 2013 to November 2018]. But for other people, their anemia may come back after Injectafer treatment. Their medical staff can help you set up another time to receive your Injectafer dose. Infusion times range from less than 20 minutes to up to 4 hours. Should I avoid certain foods while taking Venofer Vial? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. So you wont pick up this medication from a pharmacy. We comply with the HONcode standard for trustworthy health information. With slow IV injection, the drug is given as a single, slow injection into your vein. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. 2 0 obj Then the study was split into the following two groups, which are discussed below. I had Venofer infusions, 2 rounds now in the span of three years. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Best food forward: Are algae the future of sustainable nutrition? Some drugs may have another patient information leaflet. But its only approved for use in people with CKD who may or may not need dialysis. % Talk with the doctor. Injectafer can cause mild or serious side effects. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. You may report side effects to the FDA at 1-800-332-1088. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Injectafer is approved to treat iron deficiency anemia (IDA). endobj All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Before using, check this product visually for particles or discoloration. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. pain in the arms or legs. Ask your doctor or healthcare provider if Venofer is the right choice for you. An iron infusion is a way to increase the body's iron levels quickly. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). This is not a complete list of side effects and others may occur. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. With IDA, you have low hemoglobin levels. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). Its not known whether its safe to breastfeed while youre taking Injectafer. wAd**CgI%"nn{Oa[q{r5 Yes, in some cases it may. And these two doses need to be separated by at least 7 days. But for other people, their IDA returns after treatment with Injectafer. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. HRT, like other medications, does have some side effects and these are thought to be quite common. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. They can recommend appropriate treatment options. This is not a complete list of possible side effects. (IV iron is absorbed by the body more rapidly than oral iron.) Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Which tests can diagnose iron deficiency anemia? How is Venofer (iron sucrose) given? Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: For some people, it may be OK to continue taking a multivitamin that contains iron. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Iron infusion side effects vary depending on which form is being used. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Venofer is used to treat iron deficiency anemia in people with kidney disease. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Is the ketogenic diet right for autoimmune conditions? It can be given as a slow injection over 2 to 5 minutes or as an infusion. reese0809 1 yr. ago. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. This website is intended for use by US healthcare professionals only. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Tell your doctor if you are pregnant or plan to become pregnant. They can give you tips on how to deal with any side effects that may be bothersome. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. The insurance company will review the prior authorization request and decide if the drug will be covered. If you notice other effects not listed above, contact your doctor or pharmacist. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Pain, swelling, or redness at the injection site may occur. If these effects continue or worsen, tell your doctor. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? However, consuming large amounts of alcohol can actually cause anemia in some people. Tell your doctor about the allergy and what signs you had. Both Injectafer and Venofer belong to a class of medications called iron replacement products. This gives a total cumulative dose of 1,500 mg of Injectafer. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Here are answers to some frequently asked questions about Injectafer. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. For more information about Injectafers approved uses, see the section Injectafer uses below. Joint pain. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. (For more information on Venofer, see the Injectafer vs. Venofer section above). A shortage of iron can cause health problems. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. Injectafer contains the active drug ferric carboxymaltose. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Its responsible for carrying oxygen throughout your body. Venofer may reduce the absorption of iron preparations taken by mouth. . Here we look at how Injectafer and Venofer are alike and different. Low blood pressure. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Does Venofer Vial interact with other medications? One study of just under 5000 HRT users found that 43% were affected. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Venofer injection contains iron sucrose, a form of the mineral iron. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Venofer may cause significant hypotension (decreased blood pressure). The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. With IDA, you have low hemoglobin levels. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. They have been a god send. Talk to your pharmacist for more details. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Its not known how often people taking a treatment other than Injectafer had diarrhea. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Mild side effects of Injectafer can include:*. And this could lead to weight gain, if they increase their food intake. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. stream To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. If you notice any changes to your normal blood pressure, call your doctor right away. On day three I had a headache and felt heavy/exhausted, which lasted a few days. No, you most likely wont take Injectafer long term. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. fever. Phosphorus is an electrolyte that your body needs in order to make energy. With this condition, you also have a low hemoglobin level. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. These people may lose weight as their anemia improves because theyre more active. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Instead, youll start by receiving just one treatment course of Injectafer. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. The following information describes dosages that are commonly used or recommended. However, diarrhea it isnt very common in people using Injectafer. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Injectafer should be stored between 68F to 77F (20C to 25C). You may report side effects to FDA at 1-800-FDA-1088. Do not flush down a toilet or pour down a drain unless you are told to do so. Nose or throat irritation. Here we look at how Injectafer and Feraheme are alike and different. Change in taste. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Copyright 1996-2023 Cerner Multum, Inc. During Injectafer treatment, your doctor will likely order blood tests. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. Call your doctor for medical advice about side effects. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. 3 0 obj You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Heres some detail on certain side effects this drug may cause. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. It belongs to a class of medications called iron replacement products. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. I had my first infusion of 1gm 10 days ago. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Most people will metabolize medication by half every time it circulates the body. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Check with your pharmacist if you have questions about the best way to throw out drugs. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Injectafer comes as a liquid solution inside vials. In the first group, some people continued taking iron by mouth, while other people took Injectafer. This is why family members often have the same issues with drugs as others in theirfamily. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Together, they can recommend ways to help you manage a body weight thats healthy for you. Feraheme also comes as a liquid thats given by IV infusion. Call your doctor for medical advice about side effects. For example: Say you weigh 105 pounds (about 48 kilograms). Iron infusions are given directly into a vein. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. weakness. Side effects from HRT depend on a number of factors: Back pain. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. It's a more immediate treatment than supplements or dietary changes. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. <> Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. And this person had gotten their first dose of the drug without having an allergic reaction. reactions at the site of the injection. If your symptoms or health problems do not get better or if they become worse, call your doctor. Before taking Injectafer, talk with your doctor about your health history. Allergic reactions typically occur the first time your body is exposed to a drug. This information is not specific medical advice and does not replace information you receive from the healthcare provider. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. The iron released by this drug does pass into human breast milk. Details. This allows them to manage any side effects that you may have following your dose. What Is the Cost of Whole Genome Sequencing (WGS)? Injectafer contains the active drug ferric carboxymaltose. Do not double the dose to catch up. . Below are examples of these side effects. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Check with your pharmacist. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Call your doctor for medical advice about side effects. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Do not start, stop, or change the dosage of any medicines without your doctor's approval. generalized weakness. Throw away unused or expired drugs. Pain, swelling, or redness at the injection site may occur. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Blood tests may be needed to check for unwanted effects. Boxed warnings alert doctors and patients about drug effects that may be dangerous. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Iron infusion benefits. People from different ethnic backgrounds process medications differently. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. I was surprised too but the Dr said it definitely sounds like a reaction. treatment schedule in further detail. Others last much longer (even a lifetime), which can be quite traumatizing to people. But its not known whether this poses any risk to a child whos breastfed. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Consult your doctor before breast-feeding. Renal elimination is negligible. (A generic drug is an exact copy of the active drug in a brand-name medication.) For additional information, contact your healthcare provider. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. You may need extra iron because of blood loss during kidney dialysis. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. <> Youll receive doses of either drug by a healthcare professional at a medical facility. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. There have also been reports of serious allergic reactions to Venofer. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Fortunately, knowing how longside effectslast can help those suffering know what to donext. Evenbirth controlcan lead to severeside effectslike bloodclots. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. No, Injectafer itself wont make you gain weight. This survey is being conducted by the WebMD marketing sciences department. There are different types of anemia, but IDA is the most common type. The drug helps increase your hemoglobin level back to a value thats within the normal range. WebMD does not provide medical advice, diagnosis or treatment. We cancelled my 5th because of the reaction. An LSD comedown is when the mental and hallucinatory effects have worn . I used to get a different type but my . The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV.

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